Today we tend to see curiosity and imagination as two peas in a very positive pod. Yet, although they have often been linked together, neither curiosity nor the imagination has always been viewed in such a favorable light. Pandora’s curiosity supposedly unleashed all ills and calamities upon the world. In the sixteenth century, Michel de Montaigne famously called the imagination a “runaway horse” and asserted that the imagination brings fevers and death to those who give it a free hand and encourage it. How did we get from Pandora’s calamitous curiosity and Montaigne’s death-dealing imagination to Epcot Center’s gleeful celebration of curiosity and the imagination? In this course, we will seek answers to this question by looking back in time to the thought and literature of classical antiquity and Early Modern Europe–to writings by Plato, Lucian, Cervantes, Shakespeare, and others.