In this course, we examine disability from the perspective of cultural and medical anthropology. Specifically, we consider how people living with physical, mental, visible, and invisible disabilities navigate physical and social spaces, deal with prejudices of all kinds, and experience everyday life. By engaging with leading anthropologists and activists, spending time with community-based disability groups on and off campus, and studying cross-cultural scholarship, we will learn about the richness and vitality of disability worlds. Furthermore, we will look at how societal and medical conceptions of disability are changing in the context of COVID-19, human-animal entanglements, and climate change. Overall, the people we meet and material we cover emphasize the multitude of ways in which a focus on disability can generate creative modes of thinking, connection, and experience in the twenty-first century.